
Journal of Organometallic Chemistry p. 397 - 402 (1989)
Update date:2022-08-02
Topics:
Bumagin, N. A.
More, P. G.
Beletskaya, I. P.
The palladium-catalysed coupling reactions of aryl halides with acrylic acid and acrylonitrile in the presence of a base (NaHCO3 or K2CO3) in water provide a novel and efficient and very simple method for the synthesis of substituted cinnamic acids and cinnamonitriles in high yields.NaHCO3 or K2CO3 effectively acts as a base in the reaction at elevated temperature (80-100 deg C).The reaction can be carried out with higher velocity and at low temperature (50-60 deg C), using CH3COOK as a base.
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