
Tetrahedron Letters p. 8243 - 8246 (1996)
Update date:2022-08-02
Topics:
Paterson, Ian
Nowak, Thorsten
The antifungal agent (+)-restricticin (1) was prepared in 12 steps from ketone (S)-8. The key steps are (i) the boron-mediated anti aldol reaction of (S)-8 with 9 to give 13 and (ii) the cyclisation reaction 4 → 15.
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Doi:10.1016/j.tetlet.2004.03.065
(2004)Doi:10.1021/acs.joc.8b02670
(2019)Doi:10.1002/zaac.19764190305
(1976)Doi:10.1002/jlac.199719970124
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(2019)Doi:10.1055/s-1996-4410
(1996)