Bioorganic and Medicinal Chemistry Letters p. 2687 - 2692 (1996)
Update date:2022-09-26
Topics:
Weinhardt, Klaus K.
Bonhaus, Douglas W.
De Souza, Andrea
Substituted benzenesulfonyl derivatives of m-aminovalerophenones bearing a 1,3,8-triazaspiro[4.5]decane-2,4-dione at the alkyl terminus are the first known, selective ligands for the 5-HT(2C) receptor. A brief structure-activity relationship of this series is outlined.
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