Synthesis, NMR spectroscopy study, and antimuscarinic activity of a series of 2-(acyloxymethyl)-1,3-dioxolanes

DOI: 10.1016/S0968-0896(96)00223-4

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Bioorganic and Medicinal Chemistry p. 2071 - 2080 (1996)

Update date:2022-08-02

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Authors:

Malmusi, Luca

Mucci, Adele

Schenetti, Luisa

Gulini, Ugo

Marucci, Gabriella

Brasili, Livio

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Article abstract of DOI:10.1016/S0968-0896(96)00223-4

A series of 19-dioxolane-based ligands, bearing hydroxymethyl or ester functionalities, was synthesized and tested as potential muscarinic antagonists. The compounds display moderate to low affinity for the three receptor subtypes M₁-M_{3
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Full text of DOI:10.1016/S0968-0896(96)00223-4

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Article Doi

Synthesis, NMR spectroscopy study, and antimuscarinic activity of a series of 2-(acyloxymethyl)-1,3-dioxolanes

DOI: 10.1016/S0968-0896(96)00223-4

Source and publish data:

Authors:

Article abstract of DOI:10.1016/S0968-0896(96)00223-4

Full text of DOI:10.1016/S0968-0896(96)00223-4

Products guided by the article

R&D Labs maybe for 187995-84-2

Relevant to this article

Arylamide inhibitors of HIV-1 integrase

Discovery of 3-aminobenzyloxycarbonyl as an N-terminal group conferring high affinity to the minimal phosphopeptide sequence recognized by the Grb2- SH2 domain

Alkyl 2-(2-Benzoyl-2-ethoxycarbonyl-1-ethenyl)amino-3dimethylaminopropenoates in the Synthesis of Heterocyclic Systems

Synthesis and characterization of 17-valence-electron [CpCr(NO)X2]- anions: Oxidatively induced loss of the nitrosyl ligand

Sequenced Reactions with Samarium(II) Iodide. Sequential Nucleophilic Acyl Substitution/Ketyl Olefin Coupling Reactions for the Preparation of Oxygen Heterocycles

Synthesis and characterization of 17-valence-electron [CpCr(NO)X₂]^- anions: Oxidatively induced loss of the nitrosyl ligand