
Tetrahedron Letters p. 1407 - 1410 (1997)
Update date:2022-08-04
Topics:
Angelaud, Remy
Landais, Yannick
Schenk, Kurt
Sharpless asymmetric amino-hydroxylation of a silyl-2,5-cyclohexadiene occurs with complete regio- and diastereocontrol. An enantioselectivity of up to 68% e.e. was also observed. An application of the methodology to the synthesis of relevant examples of amino-cyclitols is described.
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