Synthesis and evaluation of novel oligodeoxynucleotides containing 3'- C-(3-benzoyloxypropyl)thymidine and bicyclo nucleoside derivatives

Article abstract of DOI:10.1080/07328319708006201

The stereoselective synthesis of 3'-C-Allyluridine derivative 2 has been accomplished. This nucleoside was used as a key synthon for the synthesis of oligodeoxynucleotides containing 3'-C-(3-benzoyloxypropyl)thymidine (X) or bicyclo nucleoside (Y+Z) monomers. Preliminary thermal experiments are reported.

Full text of DOI:10.1080/07328319708006201

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Nucleosides and Nucleotides
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Synthesis and Evaluation of Novel
Oligodeoxynucleotides Containing 3′-
C-(3-Benzoyloxypropyl)thymidine and
Bicyclo Nucleoside Derivatives
Henrik M. Pfundheller a , Poul Nielsen a & Jesper Wengel a
a Department of Chemistry , Odense University , DK-5230,
Odense M, Denmark
Published online: 16 Aug 2006.
To cite this article: Henrik M. Pfundheller , Poul Nielsen & Jesper Wengel (1997) Synthesis
and Evaluation of Novel Oligodeoxynucleotides Containing 3′-C-(3-Benzoyloxypropyl)thymidine
and Bicyclo Nucleoside Derivatives, Nucleosides and Nucleotides, 16:7-9, 1439-1442, DOI:
10.1080/07328319708006201
To link to this article: http://dx.doi.org/10.1080/07328319708006201
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