Synthesis and biological evaluation of 7-hydroxy-3,4-diphenyl-1,2- dihydroisoquinolines as new 4-hydroxytamoxifen analogues

DOI: 10.1248/cpb.45.939

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 939 - 943 (1997)

Update date:2022-09-26

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Authors:

Kihara, Masaru

Ikeuchi, Motoki

Yamauchi, Aiko

Nukatsuka, Mamoru

Matsumoto, Hiroshi

Toko, Toshiyuki

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Article abstract of DOI:10.1248/cpb.45.939

A phenolic 3,4-diphenyl-1,2-dihydroisoquinoline derivative (4a) as a new 4-hydroxytamoxifen analogue and a related compound (4c) were synthesized from 3,4-diphenyl-1,2,3,4-tetrahydroisoquinolin-4-ols (5a, c), which were prepared by intramolecular Barbier

Full text of DOI:10.1248/cpb.45.939

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