Stereoselective Reduction of Conjugated Homopropargylic Alcohols to (E)-Homoallylic Alcohols by Sodium Bis(2-methoxyethoxy) Aluminium Hydride

DOI: 10.1055/s-1997-926

Source and publish data:

Synlett p. 992 - 994 (1997)

Update date:2022-08-03

Topics:

Authors:

Crousse, Benoit

Alami, Mouad

Linstrumelle, Gérard

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Article abstract of DOI:10.1055/s-1997-926

The reduction of various conjugated homopropargylic alcohols with sodium bis(2-methoxyethoxy) aluminium hydride (Red-Al) in ether or THF is described. The reaction takes place cleanly and rapidly, under mild conditions, to give (E)-homoallylic alcohols st

Full text of DOI:10.1055/s-1997-926

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