Highly Stereoselective Synthesis of cis-2-Substituted-3-vinyltetrahydrofurans from (Z)-Trimethyl(5-trimethylsiloxy-2-pentenyl)silane and Acetals

Article abstract of DOI:10.1055/s-1997-3261

A variety of cis-2-substituted-3-vinyltetrahydrofurans are easily and stereoselectively produced by the reaction of acetals with (Z)-trimethyl(5-trimethylsiloxy-2-pentenyl)silane under the influence of a catalytic amount of trimethylsilyl trifluoromethanesulfonate under very mild conditions.