Tetrahedron Letters p. 5139 - 5142 (1997)
Update date:2022-08-03
Topics:
Davis, Franklin A.
Reddy, G. Venkat
Liang, Chang-Hsing
The highly stereoselective ring opening of N-tosylaziridine 2-carboxylate esters with LiAIH4 followed by oxidation of the ensuing syn alcohols results in a highly efficient 4 step asymmetric synthesis of α-methyl β-amino acids from N-sulfinylaziridine 2-carboxylate esters.
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