A Second Synthesis of D-Apio-β-D-furanosyl Maleimide as a Structural Analogue of Showdomycin

Article abstract of DOI:10.1007/BF00807603

Apioshowdomycin (3-(D-apio-β-D-furanosyl)-1H-pyrrole-2,5-dione, 2) has been prepared as an analogue of the C-nucleoside showdomycin (1) in seven steps, starting from 2,3-O-isopropylidene-D-apio-D-furanose (8). The key step is the addition of a radical gen