Total synthesis of kealiiquinone, an imidazole marine alkaloid

DOI: 10.1248/cpb.45.1393

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1393 - 1398 (1997)

Update date:2022-07-30

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Authors:

Kawasaki, Ikuo

Taguchi, Norio

Yamashita, Masayuki

Ohta, Shunsaku

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Article abstract of DOI:10.1248/cpb.45.1393

The total synthesis of kealiiquinone (1), a highly substituted imidazole marine alkaloid isolated from sponge, was achieved via nine reaction steps starting from 1-methyl-1H-imidazole (5). The synthesis is based on the selective introduction of appropriat

Full text of DOI:10.1248/cpb.45.1393

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Product name:{5-[(3,4-Dimethoxy-2-methoxymethoxy-phenyl)-methoxy-methyl]-1-methyl-2-phenylsulfanyl-1H-imidazol-4-yl}-(4-methoxy-phenyl)-methanol

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