Heteroannulation through combined palladium catalysed and Friedel-Crafts reactions strategy: Synthesis of 3-alkylidene isoindolin-1-ones

DOI: 10.1016/S0040-4020(99)00719-X

Source and publish data:

Tetrahedron p. 12361 - 12376 (1999)

Update date:2022-08-02

Topics:

Authors:

Kundu, Nitya G.

Wahab Khan

Mukhopadhyay, Rupa

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Article abstract of DOI:10.1016/S0040-4020(99)00719-X

The palladium-catalysed reactions of 2-iodobenzamides 1-5 with trimethylsilyl acetylene 6 led to 2-(2-trimethylsilyl)ethynyl benzamides 7-11 in excellent yields. The 2-(2-trimethylsilyl)ethynyl benzamides 7-11 underwent Friedel-Crafts reactions with acid

Full text of DOI:10.1016/S0040-4020(99)00719-X

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Product name:2-[(2'-trimethylsilylethynyl)-N-m-chlorophenyl]benzamide

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