Bioorganic and Medicinal Chemistry Letters p. 2223 - 2226 (1998)
Update date:2022-07-29
Topics:
Liddle, John
Huffman, John W.
Wiley, Jenny L.
Martin, Billy R.
An enantioselective synthesis of the (1'S,2'R)-dimethylheptyl cannabinoid side chain has been developed and employed in the synthesis of 11-hydroxy-(1'S,2'R)-dimethylheptyl-Δ8-THC (3). Pharmacology, in vivo and in vitro, indicate (3) to be one of the most potent traditional cannabinoids known.
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(1998)Doi:10.1021/acs.jmedchem.7b00264
(2017)Doi:10.1039/d0ob01815e
(2020)Doi:10.1021/om9705665
(1998)Doi:10.1016/0031-9422(88)84097-4
(1988)
