Bioorganic and Medicinal Chemistry Letters p. 2223 - 2226 (1998)
Update date:2022-07-29
Topics:
Liddle, John
Huffman, John W.
Wiley, Jenny L.
Martin, Billy R.
An enantioselective synthesis of the (1'S,2'R)-dimethylheptyl cannabinoid side chain has been developed and employed in the synthesis of 11-hydroxy-(1'S,2'R)-dimethylheptyl-Δ8-THC (3). Pharmacology, in vivo and in vitro, indicate (3) to be one of the most potent traditional cannabinoids known.
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(1988)
