Solution-phase synthesis of 2,6,9-trisubstituted purines

DOI: 10.1016/S0040-4039(98)00098-7

Source and publish data:

Tetrahedron Letters p. 1827 - 1830 (1998)

Update date:2022-08-04

Topics:

Authors:

Fiorini, Maria T.

Abell, Chris

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Article abstract of DOI:10.1016/S0040-4039(98)00098-7

A simple three-step method for the solution-phase combinatorial synthesis of 2,6,9-trisubstituted purines from 2,6-dichloropurine is described. The synthesis exploits the use of resin capture to remove excess reagent used in the final step.

Full text of DOI:10.1016/S0040-4039(98)00098-7

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