A highly selective synthesis of α-monofluoro- and α-monochloro- benzylphosphonates using eiectrophilic halogenation of benzylphosphonates carbanions

Article abstract of DOI:10.1016/S0040-4039(98)00648-0

The selective electrophilic monofluorination and monochlorination of a wide variety of diethyl benzylphosphonates have been realized in a one-pot procedure. The monohalogenation was accomplished by intermediate of a benzylic carbanion protected with TMSCl