N-[4-(1,1'-biphenyl)methyl]-4-(4-thiomorpholinylmethyl) benzenamines as non-oxazolidinone analogues of antimycobacterial U-100480

DOI: 10.1016/S0960-894X(98)00248-0

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1493 - 1498 (1998)

Update date:2022-07-29

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Authors:

Artico, Marino

Mai, Antonello

Sbardella, Gianluca

Massa, Silvio

Lampis, Giorgio

Deidda, Delia

Pompei, Raffaello

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Article abstract of DOI:10.1016/S0960-894X(98)00248-0

Thiomorpholine analogues of U-100480 with the biphenylmethyl group replacing the acetamidomethyloxazolidinone moiety have been synthesized and tested as antimycobacterial agents together with various related derivatives. Some biphenyl derivatives were endowed with high activity against Mycobacterium tuberculosis and other non-tuberculous mycobacteria.

Full text of DOI:10.1016/S0960-894X(98)00248-0

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