Synthesis and in vitro cytotoxicity of C(20)(RS)-camptothecin analogues modified at both B (or A) and E ring

DOI: 10.1016/S0960-894X(98)00317-5

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1797 - 1800 (1998)

Update date:2022-09-26

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Authors:

Jew, Sang-Sup

Kim, Myoung Goo

Kim, Hee-Jin

Rho, Eun-Young

Park, Hyeung-Geun

Kim, Joon-Kyum

Han, Hyun-Jung

Lee, Heesoon

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Article abstract of DOI:10.1016/S0960-894X(98)00317-5

A series of C(7) and C(20)-substituted camptothecin derivatives (12 - 14, 16 - 18) are prepared. Their syntheses and in vitro cytotoxicities are reported.

Full text of DOI:10.1016/S0960-894X(98)00317-5

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