Tetrahedron Letters p. 2633 - 2636 (1999)
Update date:2022-07-31
Topics:
Hollingworth, Gregory J.
Dinnell, Kevin
Dickinson, Laura C.
Elliott, Jason M.
Kulagowski, Janusz J.
Swain, Christopher J.
Thomson, Christopher G.
A general method for the synthesis of cyclopropyl ethers from phenols is described. Alkylation of a phenol using 1-iodo-1-(phenylthio)cyclopropane followed by removal of the phenylthio group furnishes the cyclopropyl ethers in modest to excellent yields. The procedure tolerates a wide range of functional groups.
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