Diastereoselective 1,3-dipolar cycloaddition of nitrilimines to γ-oxygenated α,β-unsaturated enones and esters

Article abstract of DOI:10.1016/0957-4166(96)00119-X

The stereochemical outcome of the 1,3-dipolar cycloaddition of nitrilimines to γ-oxygenated α,β-unsaturated enones and esters was investigated. By means of X-ray and NMR analysis the main diastereomers were assigned as the syn-derivatives. Novel enantiomerically pure nitrilimines were included in the investigations but did not influence the stereochemical course of the cycloaddition significantly.