An efficient stereoselective and stereodivergent synthesis of (2R,3R)- and (2R,3S)-3-hydroxypipecolic acids

DOI: 10.1016/S0040-4039(00)01207-7

Source and publish data:

Tetrahedron Letters p. 7033 - 7036 (2000)

Update date:2022-08-05

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Authors:

Jourdant

Zhu Zhu

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Article abstract of DOI:10.1016/S0040-4039(00)01207-7

Asymmetric syntheses of (2R,3R) and (2R,3S)-3-hydroxypipecolic acids are reported featuring a key diastereoselective addition of Buchi's Grignard reagent to the chiral serinal L-5. Based on conformational analysis, a stereocontrolled reduction of piperidi

Full text of DOI:10.1016/S0040-4039(00)01207-7

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