Journal of the American Chemical Society p. 3875 - 3884 (2002)
Update date:2022-09-26
Topics:
Thomas, Craig J.
McCormick, Michael M.
Vialas, Corine
Tao, Zhi-Fu
Leitheiser, Christopher J.
Rishel, Michael J.
Wu, Xihan
Hecht, Sidney M.
The bleomycin (BLM) group of antitumor antibiotics effects DNA cleavage in a sequence-selective manner. Previous studies have indicated that the metal-binding and bithiazole moieties of BLM are both involved in the binding of BLM to DNA. The metal-binding
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