Synthesis of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid analogues modified at the C-4 and C-9 positions and their behaviour towards sialidase from influenza virus and pig liver membrane

DOI: 10.1016/S0008-6215(00)00267-6

Source and publish data:

Carbohydrate Research p. 31 - 41 (2001)

Update date:2022-09-26

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Authors:

Ikeda, Kiyoshi

Sano, Kimihiko

Ito, Masaki

Saito, Megumi

Hidari, Kazuya

Suzuki, Takashi

Suzuki, Yasuo

Tanaka, Kiyoshi

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Article abstract of DOI:10.1016/S0008-6215(00)00267-6

The synthesis of novel 2-deoxy-2,3-didehydro-N-acetylneuraminic acid analogues structurally varied at C-4 and C-9 by transformation from versatile key intermediates and their inhibitory activity against sialidase from influenza virus A and pig liver membrane are described.

Full text of DOI:10.1016/S0008-6215(00)00267-6

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