Bioorganic and Medicinal Chemistry Letters p. 2999 - 3002 (1996)
Update date:2022-07-31
Topics:
Cheng
Lee
Klutchko
Winters
Reynolds
Welch
Flynn
Doherty
Screening of a compound library against endothelin receptors (ET(A) and ET(B)) revealed PD 102566 (compound 1) as an ET(A) selective antagonist. Synthesis and structure-activity relationships (SAR) of a series of analogs are described.
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