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S. D. Bull et al. / Tetrahedron: Asymmetry 12 (2001) 2941–2945
Acknowledgements
The authors wish to acknowledge the support of the
EPSRC and Rhoˆne Poulenc Rorer for a CASE Award
(A.D.S.) and New College, Oxford for a Junior
Research Fellowship (A.D.S.).
References
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Scheme 3. Reagents and conditions: (i) (R)-2 (1.6 equiv.),
THF, −78°C; (ii) NEt3, tert-butyl acrylate, Pd(OAc)2, tri-o-
tolylphosphine; (iii) (S)-17 (3 equiv.), THF, −78°C.
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Scheme 4. Reagents and conditions: (i) Rh(PPh3)3Cl,
MeCN:H2O (8.5:1.5), D; (ii) Cbz2O, vacuum, rt; (iii) HCO2H,
60°C.