Journal of labelled compounds and radiopharmaceuticals p. 79 - 89 (2002)
Update date:2022-07-30
Topics:
Reddy, Pulgam Veera
Rabago-Smith, Monsterrat
Borhan, Babak
The enzyme, 15, 15′-β-carotene dioxygenase (BCDOX), facilitates the oxidation of β-carotene to yield retinal. This is a remarkable process in which one of 11 double bonds in β-carotene is selectively oxidized. To further probe the mechanistic aspects of BCDOX, the synthesis of all-trans-[10′-3H]-8′-apo-β-carotenoic acid is reported. This compound will be used as a photoaffinity labeling reagent to probe the β-carotene binding pocket within BCDOX. The synthesis outlines a simple and efficient route for the incorporation of tritium at the 10′ olefinic carbon of 8′-apo-β-carotenoic acid. Copyright
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Doi:10.1055/s-1978-24685
(1978)Doi:10.1021/ja01114a506
(1953)Doi:10.1023/A:1023998420937
(2003)Doi:10.1021/ja202732q
(2011)Doi:10.1177/000992280104000707
(1891)Doi:10.1021/jo0504767
(2005)