ASYMMETRIC INDUCTION BY CHIRAL SILICON GROUPS

Article abstract of DOI:10.1016/0022-328X(85)80241-2

The reduction of racemic RPhMeSiCCl2CH3 systems (R=cyclohexyl, isoprpyl, t-butyl and 2-mesityl) to the diastereomeric RPhMeSiCHClCH3 with tributyltin hydride was used as a probe into the potential of the RPhMeSi group to induce asymmetry at an α position.Favorable results were obtained for R=mesityl.