Electrostatic and allosteric cooperativity in ion-pair binding: A quantitative and coupled experiment-theory study with aryl-triazole-ether macrocycles

Article abstract of DOI:10.1021/jacs.5b05839

Cooperative binding of ion pairs to receptors is crucial for the manipulation of salts, but a comprehensive understanding of cooperativity has been elusive. To this end, we combine experiment and theory to quantify ion-pair binding and to separate alloste