Nucleotides, XVIII. Synthesis and Properties of (tert-Butyldimethylsilyl)guanosines, Guanosine-3'-Phosphotriesters and Guanosine-containing Oligonucleotides

Article abstract of DOI:10.1002/hlca.19830660718

Silylation of N²-benzoyl- (1) and N²-isobutyrylguanosin (2) by tert-butyldimethylsilyl chloride led to the various mono-, di- and tri-O-tert-butyldimethylsilyl derivatives 3-15.The synthesis of 2'- (24-31) and 3'-phosphotriesters (16