Studies on Cycloimmonium Ylides: Synthesis of Some New 2,4,6-Trisubstituted Pyridines. 2

Article abstract of DOI:10.1021/je60086a032

A wide range of 2,6-di(thienyl)-4-arylpyridines, 2-(4-biphenyl)-4-aryl-6-(2-thienyl)pyridines, and 2-(4-biphenyl)-4-aryl-6-(2-naphthyl)pyridines have have been synthesized by the interaction of 1-(2-thiophenoylmethyl)pyridinium iodide, 1-(4-phenylphenacyl)pyridinium bromide, and 1-(2-naphthoylmethyl)pyridinium bromide with a variety of α,β-unsaturated ketones.Ammonium acetate in glacial acetic acid was used as cyclization agent.The structures of the resulting products were confirmed by IR and NMR spectral analyses.