Identification in human urine of Δ9-tetrahydrocannabinol-11-oic acid glucuronide: a tetrahydrocannabinol metabolite

Article abstract of DOI:10.1111/j.2042-7158.1980.tb12966.x

A Δ⁹-THC metabolite has been identified in human urine as an ester linked glucuronide of Δ⁹-THC-11-oic acid. Its identity was established by a comparison of mass spectra from the metabolite extracted from human urine and synthetically prepared material. Δ⁹-THC-11-oic acid glucuronide was found to be responsible for the major part of RIA cross-reactivity in urine with the Guildhay cannabinoid antiserum used in this study.