The Friedel-Crafts arylation of α-substituted chalcones revisited: Highly stereospecific synthesis of trans-2,3-diphenyl-indan-1-one derivatives

Article abstract of DOI:10.1080/00397919608004661

The Lewis or protic acid promoted cycloisomerization of 1,2,3-triphenylpropenone in nitroethane as solvent has given trans-2,3-diphenyl-indan-1-one with complete diastereoselection in good to excellent chemical yield.

Full text of DOI:10.1080/00397919608004661

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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The Friedel-Crafts Arylation
of α-Substituted Chalcones
Revisited: Highly Stereospecific
Synthesis of TRANS-2,3-
Diphenyl-Indan-1-One
Derivatives
José L. Marco a
a Instituto de Química Orgánica General, (CSIC) ,
Juan de la Cierva, 3, 28006, Madrid, Spain
Published online: 19 Aug 2006.
To cite this article: José L. Marco (1996) The Friedel-Crafts Arylation of α-Substituted
Chalcones Revisited: Highly Stereospecific Synthesis of TRANS-2,3-Diphenyl-
Indan-1-One Derivatives , Synthetic Communications: An International Journal
for Rapid Communication of Synthetic Organic Chemistry, 26:22, 4225-4231, DOI:
10.1080/00397919608004661
To link to this article: http://dx.doi.org/10.1080/00397919608004661
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