Journal of Organic Chemistry p. 3223 - 3226 (1981)
Update date:2022-09-26
Topics:
Snider, Barry B.
Duncia, John V.
Both diastereomers of 2-amino-4-methyl-5-hexenoic acid (7 and 16) have been synthesized stereospecifically from methyl (2R*,4S*)-2-bromo-4-methyl-5-hexenoate (1), the product of the EtAlCl2-catalyzed ene reaction of methyl α-bromoacrylate and trans-2-butene.This synthesis establishes the stereochemistry of the ene reaction and establishes that the amino isolated from a Streptomyces fermentation is 7.
View Morewebsite:http://www.chemdow.com
Contact:0086-10-82435335
Address:Room 401,Unit 3,4th Floor,Shangdijiayuan,Shangdi East Road, Haidian District,Beijing
website:http://www.biet.com.cn/
Contact:+86-27-8369 8488
Address:No. 6, Building 21, China Merchants Fanwang, Sixin North Road, Hanyang District, Wuhan City, Hubei Province
Wuhan Hanye Chemical New Material Co.,Ltd
Contact:+86-27-85308141
Address:LiuDian, Panlongcheng Economic Development Zone, HuangPi district, Wuhan, Hubei 430311 P.R.China
Contact:86 21 3772 9386
Address:Rm.1803,Starry Bldg.1,1505 Meijiabang Road,Shanghai 201620 China
Hangzhou Yanshan Chemical Co.,Ltd.
Contact:86-571- 87698076
Address:Room 1001, #1 Building, Zhongtian MCC, No.2 Youzhinong, Wenyi West Road, Xihu District, Hangzhou, China
Doi:10.1016/j.tet.2017.05.080
(2017)Doi:10.1080/00397911.2014.905600
(2014)Doi:10.1016/S0040-4039(01)97428-3
(1971)Doi:10.1039/c39930000864
(1993)Doi:10.1021/jo00076a048
(1993)Doi:10.1039/c39810000142
(1981)
