Journal of Organic Chemistry p. 4010 - 4012 (1993)
Update date:2022-08-02
Topics: Analogues Kinetic Resolution Lipase-Catalyzed N-protected Statine
Baenziger, Markus
McGarrity, John F.
Meul, Thomas
A new synthesis of N-protected statine 4a and its analogue 4b is presented. cis-(+/-)-Butyric acid 2-isobutyl-5-oxopyrrolidin-3-yl ester (10a) and cis-(+/-)-butyric acid 2-benzyl-5-oxopyrrolidin-3-yl ester (10b) were prepared from methyl (E)-4-chloro-3-me
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