Journal of Medicinal Chemistry p. 167 - 171 (1982)
Update date:2022-08-05
Topics:
Robertson, David W.
Katzenellenbogen, John A.
Hayes, James R.
Katzenellenbogen, Benita S.
A series of N-substituted (Z)-1,2-diphenyl-1-<4-(2-aminoethoxy)phenyl>-1-butenes, analogues of the antiestrogen tamoxifen (Nolvadex), in which the side-chain basicity is varied over a wide range, has been prepared to probe the importance of basicity in ev
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