USEFUL SYNTHETIC REAGENTS DERIVED FROM 1-TRIISOPROPYLSILYLPROPYNE AND 1,3-BISPROPYNE. DIRECT, STEREOSELECTIVE SYNTHESIS OF EITHER Z OR E ENYNES

Article abstract of DOI:10.1016/S0040-4039(00)86930-0

Lithio reagents derived from 1-triisopropylsilylpropyne (1) and 1,3-bis-propyne (3) are effective for the synthesis of Z or E terminal enyne units (CH=CH-C<*>CH) and for carbon-carbon bond formation with halides, aldehydes, ketones, epoxides, and α,β-enones.