Preferential Introduction of a Pyridylmethyl Group into Sulfonamides as an Approach to an Intramolecular Transimination

Article abstract of DOI:10.1246/bcsj.55.2153

N,N'-Bis(p-tolylsulfonyl)-α,ω-alkanediamine disodium salts (n=3, 4, 5, 6, 7, 8, 9, 10) were subjected to monopyridylmethylation by the reaction with 5'-deoxy-5'-chloro- or 5'-deoxy-2'-chloro-3,4'-O-isopropylidenepyridoxine hydrochloride, accompanied by th