Journal of the Chemical Society. Perkin transactions II p. 721 - 725 (1983)
Update date:2022-08-05
Topics:
Lub, Johan
Beekes, Marinus L.
Boer, Thymen J. de
Trimethylaluminium does not methylate 1-chloro-1-nitroso-2,2,6,6-tetramethylcyclohexane (I), but functions as an electron donor and initiator of radical reactions that lead ultimately to products (II)-(V), oxime derivatives, and an imine as outlined in reaction (1).E.s.r. studies support the intermediacy of iminyl radical (VI) which can undergo ring opening to the cyano-substituted radical (VII).For a kinetic e.s.r. study of this isomerisation the iminyl radical (VI) was generated from the diphenylmethyl oxime ether (XI) by reaction with t-butoxyl radicals.Combination of radical (VII) with iminoxyl radicals gives rise to oxime ether (IV).The same product can be obtained by photolysis of the oxalate (XIII) and this supports the radical nature of the process.
View MoreSuzhou Lixin Pharmaceutical Co., Ltd.
Contact:86-512-88169812
Address:21 Tangxi Road, Suzhou New District, Suzhou 215151
Beijing Mesochem Technology Co.,LTD
website:http://www.mesochem.com
Contact:0086-10-57862036
Address:2301, Floor 23, Building 9 Lippo Plaza, Yard 8 Ronghua Middle Road, ETDZ, Beijing, China
Wuhan Benjamin Pharmaceutical Chemical Co.,Ltd
Contact:86-27-52341789
Address:Room 1518 B suite, optical valley time square, No 111 Guanshan Road, Hongshan District,Wuhan,Hubei Province,China.
Contact:+86-574-89075960
Address:#100 Xiang Yun Road, New High tech area, Ningbo, China
Contact:0510-85393305
Address:1619 Huishan Avenue, Huishan District, Wuxi,
Doi:10.1016/j.tet.2005.06.004
(2005)Doi:10.1021/jo00164a003
(1983)Doi:10.1021/ol051433f
(2005)Doi:10.1016/j.tetlet.2005.05.145
(2005)Doi:10.1016/S0040-4039(00)81611-1
(1983)Doi:10.1246/bcsj.56.499
(1983)
