Quinazolines and 1,4-benzodiazepines. XCIV. Pyrazino[1,2-a][1,4]benzodiazepines

DOI: 10.1002/jhet.5570200357

Source and publish data:

Journal of Heterocyclic Chemistry p. 791 - 793 (1983)

Update date:2022-08-03

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Authors:

Walser Walser

Flynn Flynn

Fryer Fryer

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Article abstract of DOI:10.1002/jhet.5570200357

A series of pyrazino[1,2-a][1,4]benzodiazpines were prepared by acylating the primary amino group of an α-amino-1,4-benzodiazepine-2-ylideneacetic acid ester (1) with α-chloroacyl chlorides followed by cyclodehydrohalogenation with triethylamine in dimeth

Full text of DOI:10.1002/jhet.5570200357

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