Quinazolines and 1,4-benzodiazepines. XCIV. Pyrazino[1,2-a][1,4]benzodiazepines

DOI: 10.1002/jhet.5570200357

Source and publish data:

Journal of Heterocyclic Chemistry p. 791 - 793 (1983)

Update date:2022-08-03

Topics:

Authors:

Walser Walser

Flynn Flynn

Fryer Fryer

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/jhet.5570200357

A series of pyrazino[1,2-a][1,4]benzodiazpines were prepared by acylating the primary amino group of an α-amino-1,4-benzodiazepine-2-ylideneacetic acid ester (1) with α-chloroacyl chlorides followed by cyclodehydrohalogenation with triethylamine in dimeth

Full text of DOI:10.1002/jhet.5570200357

Products guided by the article

Product name:[7-Chloro-5-(2-chloro-phenyl)-1,3-dihydro-benzo[e][1,4]diazepin-(2Z)-ylidene]-(2-chloro-propionylamino)-acetic acid methyl ester

Cas No:87216-21-5

R&D Labs maybe for 87216-21-5

shanghai payne pharm co.,ltd.

Contact:+86-021-58123769

Address:No.780 of Cailun Road,Zhangjiang Hi-tech Park,Pudong,Shanghai
Shanghai birch chemical technology co.,ltd

Contact:+86-21-54096810

Address:No.2588,Jungong Road,Shanghai,China
Onlychem (Jinan)Biotech Co.,Ltd

Contact:86-531-83175885

Address:No. 44, Honglou South Road, Jinan,China
Zipont chem(wuhan）Tech co.，Ltd

Contact:+86-27-87587198

Address:wuhan
Shanghai Yuantai Chemical Products Co., Ltd

Contact:021--66129803

Address:Chengyin Road,Shanghai,China

Relevant to this article

Synthesis and preliminary biological evaluation of (2S,1′R,2′S) - and (2S,1′S,2′R)-2-(2′-phosphonocyclopropyl)glycines, two novel conformationally constrained L-AP4 analogues

Doi:10.1016/j.bmcl.2005.09.014
(2006)
An easy approach for the acetylation of saccharidic alcohols. Applicability for regioselective protections

Doi:10.1016/S0040-4039(03)01072-4
(2003)
Chemistry of Substituted (α-Carbethoxyvinyl)cuprates. 2. Stereospecific Olefin Synthesis

Doi:10.1021/jo00172a036
(1983)
Structure-activity relationships of non-imidazole H₃ receptor ligands. Part 3: 5-Substituted 3-phenyl-1,2,4-oxadiazoles as potent antagonists

Doi:10.1016/j.bmcl.2003.11.038
(2004)
Synthesis and interactions of 7-deoxy-, 10-deacetoxy, and 10-deacetoxy-7-deoxypaclitaxel with NCI/ADR-RES cancer cells and bovine brain microvessel endothelial cells

Doi:10.1016/j.bmcl.2005.09.043
(2006)
Conversion of β-Hydroxyglutarohydroxamates to Carbapenem Precursors

Doi:10.1021/jo00171a062
(1983)

Article Doi