Journal of Medicinal Chemistry p. 6888 - 6904 (2011)
Update date:2022-08-02
Topics:
Glossop, Paul A.
Watson, Christine A. L.
Price, David A.
Bunnage, Mark E.
Middleton, Donald S.
Wood, Anthony
James, Kim
Roberts, Dannielle
Strang, Ross S.
Yeadon, Michael
Perros-Huguet, Christelle
Clarke, Nicholas P.
Trevethick, Michael A.
MacHin, Ian
Stuart, Emilio F.
Evans, Steven M.
Harrison, Anthony C.
Fairman, David A.
Agoram, Balaji
Burrows, Jane L.
Feeder, Neil
Fulton, Craig K.
Dillon, Barry R.
Entwistle, David A.
Spence, Fiona J.
A novel tertiary amine series of potent muscarinic M3 receptor antagonists are described that exhibit potential as inhaled long-acting bronchodilators for the treatment of chronic obstructive pulmonary disease. Geminal dimethyl functionality pr
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