NEW STRATEGY FOR RACEMIZATION OF 2-AMINO-1,3-PROPANEDIOLS, KEY INTERMEDIATES FOR THE SYNTHESIS OF ANTIBIOTIC DRUGS

DOI: 10.1016/S0040-4039(00)80813-8

Source and publish data:

Tetrahedron Letters p. 5561 - 5564 (1988)

Update date:2022-09-26

Topics:

Authors:

Giordano, Claudio

Cavicchioli, Silvia

Levi, Silvio

Villa, Marco

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Article abstract of DOI:10.1016/S0040-4039(00)80813-8

A new strategy for racemization of the 2-amino-1,3-propanediol 2b, based on a chemoselective oxazoline ring formation and a highly diastereoselective reduction of the ketone 4 is reported.

Full text of DOI:10.1016/S0040-4039(00)80813-8

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