Journal of Organic Chemistry p. 1900 - 1904 (1985)
Update date:2022-08-03
Topics:
Bobowski, George
Yates, Peter
Condensation of 1,1-diphenyl-2-propanone with methyl- and ethylamine hydrochloride and a large excess of paraformaldehyde in refluxing methanol gave 1-alkyl-3,3-diphenyl-4-piperidinones (1) as the main isolable products.When the reaction was carried out at 120 deg C, there resulted dimeric compounds 1,6'-dialkyl-3',4',5',6',7',8'-hexahydro-5,5,8',8'-tetraphenylspiro
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Doi:10.1021/ja01060a041
(1964)Doi:10.1007/BF02909767
(1958)Doi:10.1021/ja00296a040
(1985)Doi:10.1021/jm00171a046
(1990)Doi:10.1055/s-1985-31113
(1985)Doi:10.1271/bbb.100124
(2010)