A New Mild Oxidation of Amines to Aldehydes and Ketones. Part II

Article abstract of DOI:10.1016/S0040-4039(00)82432-6

The silylamines 1, after conversion into their lithium or zinc salts, were readily oxidized by dry air under very mild conditions (-60 deg C to -20 deg C; 5-45 min.) into the corresponding aldehydes or ketones 2 in good yields.Our reaction conditions tolerate the presence of other oxidation sensitive functional groups like a phosphine, a thioether or a tertiary amine.