Preparation of α-Bromo- and α-Chlorocarboxylic Acids from α-Amino Acids

Article abstract of DOI:10.1002/hlca.19830660404

Diazotization of α-amino acids in 48:52 (w/w) hydrogen fluoride/pyridine along with excess of potassium halide results in the corresponding α-halocarboxylic acids in good to excellent yields (Table 1 and 2).