Boron trifluoride induced fragmentation of β-Aryl-β-hydroxyketones

DOI: 10.1016/S0040-4039(98)01777-8

Source and publish data:

Tetrahedron Letters p. 8071 - 8072 (1998)

Update date:2022-08-16

Topics:

Authors:

Kabalka, George W.

Tejedor, David

Li, Nan-Sheng

Reddy, Malladi

Trotman, Sarah

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Article abstract of DOI:10.1016/S0040-4039(98)01777-8

β-Aryl-β-hydroxy ketones are readily cleaved by boron trifluoride in non-protic solvents. The reaction appears to proceed via a non-synchronous Grobe fragmentation pathway.

Full text of DOI:10.1016/S0040-4039(98)01777-8

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