
Heterocyclic Communications p. 17 - 23 (2007)
Update date:2022-08-17
Topics:
Harris, Dorothy
Stewart, Michelle
Sielaff, Alan
Mulder, Keith
Brown, Toni
Mackay, Hilary
Lee, Moses
Hairpin imidazole (I)- and pyrrole (P)-containing polyamide analogs of distamycin that bind at specific sequences in the minor groove of DNA are potentially useful gene control agents. There is a pressing need for efficient syntheses of such polyamides. The syntheses of four specific hexaheterocyclic hairpin polyamides (PIP- γ -PPP 1, PIP- γ -PII 2, PIP- γ -III 3, and PIP- γ -IPI 4, γ represents 4-aminobutyrate) using a solution phase approach are reported.
View More
Tianjin Crest Pharmaceutical R&D Co., Ltd. (Tianjin Yao Technology Development Co., Ltd.)(expird)
Contact:+86-22-66211386
Address:Building B5-405, No, 80 4th Avenue, TEDA, Tianjin, China P.R. 300457
ShangHai Original Economy-Trade Develop Co.,Ltd.,
Contact:86-21-68552131
Address:shanghai
Zhejiang Allied Chemical Co.,Ltd
Contact:18967038207
Address:Area A-30, High-tech Industrial Park, Quzhou, Zhejiang, China.
Contact:+86-574-87065746
Address:10th Floor, No.787 Baizhang East Road,
Beijing Mediking Biopharm Co., Ltd.
Contact:+86-10-89753524/81760121/81769521
Address:Hongxianghong Incubator, Beiqijia Town, Changping district, Beijing, China
Doi:10.1246/cl.1984.1913
(1984)Doi:10.1021/jm00099a023
(1992)Doi:10.1016/j.phytochem.2006.03.008
(2006)Doi:10.1039/a700261k
(1997)Doi:10.1016/S0040-4020(01)97799-3
(1960)Doi:10.1039/a906020k
(1999)