An improved practical synthesis of leuco-1,4,5,8-tetrahydroxyanthraquinone

Article abstract of DOI:10.1080/00397919508015864

Leuco-1,4,5,8-tetrahydroxyanthraquinone was prepared from chrysazin by nitration and reduction with iron powder, followed by treatment with sodium hydrosulfite in alkaline solution. This method is suitable for scaling, and is significant and improved over literature methods.

Full text of DOI:10.1080/00397919508015864

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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An Improved Practical
Synthesis of Leuco-1,4,5,8-
Tetrahydroxyanthraquinone
Pong Chang a b c & Chia Chung Cheng a b c
a School of Pharmacy, National Defense Medical
Center, Taipei, 100, Taiwan, R.O.C.
b Drug Development Laboratory, University of Kansas
Cancer Center, Kansas City, KS, 66160-7419, U.S.A.
c Department of Pharmacology, Toxicology &
Therapeutics, The University of Kansas Medical
Center, Kansas City, KS, 66160-7419, U.S.A.
Published online: 23 Sep 2006.
To cite this article: Pong Chang & Chia Chung Cheng (1995) An Improved Practical
Synthesis of Leuco-1,4,5,8-Tetrahydroxyanthraquinone, Synthetic Communications: An
International Journal for Rapid Communication of Synthetic Organic Chemistry, 25:13,
1893-1900, DOI: 10.1080/00397919508015864
To link to this article: http://dx.doi.org/10.1080/00397919508015864
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