Journal of Pharmaceutical Sciences p. 1181 - 1182 (1979)
Update date:2022-08-17
Topics:
Yost
Holtzman
Two improvements in propranolol resolution were developed. Both the (+)- and (-)-di-(p-toluoyl)tartaric acids were used as the resolving agents. This procedure reduced the number of crystallizations needed to obtain a pure product. Furthermore, synthesis of the resolving agent was improved.
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