INORGANIC AND NANO-METAL CHEMISTRY
5
8. Varala, R.; Enugala, R.; Ponnamanemi, V. K.; Adapa, S. R. One
Pot Reduction of Imines Generated in-Situ from Aldehydes and
Amines by the NaBH4-InCl3 System. Chin. J. Chem. 2006, 24,
9. Haskelberg, L. Aminative Reduction of Ketones. J. Am. Chem.
electron withdrawing (–Cl and –NO2) and electron donating
(–CH3, –OCH3 and –OH) groups in their side chains didn’t
interfere the course of the reaction. The reduction was com-
plete within 2–4 h and the yield of the reaction was in the
range of 85–97%.
10. Abiraj, K.; Dinesh, B.; Srinivasa, G. R.; Channe Gowda, D.
Catalytic Transfer Hydrogenation of Imines to Secondary
Amines Using Inexpensive Commercial Zinc Dust and
Ammonium Formate. J. Chem. Res. 2006, 2006, 534–535. DOI:
11. Yang, Y.; Liu, S.; Li, J.; Tian, X.; Zhen, X.; Han, J. Convenient
Method for Reduction of C-N Double Bonds in Oximes, Imines
and Hydrazones Using Sodium Borohydride-Raney Ni System.
12. Amado Sierra, M. d R. I. Palladium-Catalyzed PMHS Reductions
of Imines. Master of Science Thesis, Michigan State University,
Conclusion
In summary, an easy and cost-effective protocol was demon-
strated for the catalytic transfer hydrogenation of Schiff
bases using biosynthesized nickel oxide nanoparticles as het-
erogeneous catalyst. The influence of various reaction
parameters such as catalyst, temperature, solvent and the
catalyst loading on the reduction of imines was examined.
The results implied that the biosynthesized NiO nanopar-
ticles reduced imines with minimum amount (1 mg) of the
catalyst loading and good reusability of the catalyst was
demonstrated.
13. Takale, B. S.; Tao, S. M.; Yu, X. Q.; Feng, X. J.; Jin, T.; Bao, M.;
Yamamoto, Y. Exclusive Chemoselective Reduction of Imines in
the Coexistence of Aldehydes Using AuNpore Catalyst. Org. Lett.
Funding
This work was supported by DST-SERB, India under Grant
(ECR/2016/001523).
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14. Poreddy, R.; Garcıa-Suarez, E. J.; Riisager, A.; Kegnaes, S. Silver
Nanoparticles Supported on Alumina-a Highly Efficient and
Selective Nanocatalyst for Imine Reduction. Dalton Trans. 2014,
15. Malkov, A. V.; Figlus, M.; Cooke, G.; Caldwell, S. T.; Rabani, G.;
Prestly, M. R.; Kocovsky, P. Organocatalysts Immobilised onto
Gold Nanoparticles: Application in the Asymmetric Reduction of
Imines with Trichlorosilane. Org. Biomol. Chem. 2009, 7,
16. Ali, S.; Faezeh, S.; Hossein, E.; Iman, K. Nano-Sized NiLa2O4-
NaBH4-Mediated Reduction of Imines to Secondary Amines.
17. Muthuvinothini, A.; Stella, S. Green Synthesis of Metal Oxide
Nanoparticles and Their Catalytic Activity for the Reduction of
Aldehydes. Process. Biochem. 2019, 77, 48–56. DOI: 10.1016/j.
18. Paquin, L.; Hamelin, J.; Francoise, T.-B. Efficient Microwave-
Assisted Solvent-Free Synthesis of N-Substituted Aldimines.
19. Xavier, A.; Srividhya, N. Synthesis and Study of Schiff Base
20. Rahdar, A.; Aliahmad, M.; Azizi, Y. NiO Nanoparticles:
Synthesis and Characterization. JNS 2015, 5, 145–151. DOI: 10.
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