Tetrahedron p. 11055 - 11064 (1993)
Update date:2022-08-29
Topics:
Moree, Wilna J.
Marel, Gijs A. van der
Boom, Jacques H. van
Liskamp, Rob M. J.
A convenient route towards the synthesis of peptides containing the methylphosphinamide moiety as a novel transition-state isostere of the amide bond hydrolysis is described.The key step being the coupling of a methylphosphinic chloride with an amino acid
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